113 results
Benzodiazepines: Mechanism of Action and Side Effects
 • Decr spinal cord activity -> Muscle relaxant
Decr spinal cord activity ... amygdala-centered circuit activity ... -> Decr fear, Decr ... cerebral cortex activity ... #Pharmacology #pathophysiology
Subjective Tinnitus: Pathogenesis and clinical findings
Subjective Tinnitus - Perceived sound with no acoustic stimulus, heard only
structures in or near ... the ear, perceived ... Tinnitus #Causes #pathophysiology ... #differential #diagnosis
Tuberculosis Testing

LATENT TB
• LTBI is diagnosed when an asymptomatic patient has a positive TST or IGRA
TB • LTBI is diagnosed ... • The goal of diagnosing ... sputum • Improves diagnostic ... Tuberculosis #Testing #Diagnosis ... #InfectiousDiseases
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
injury -> Ligaments tear ... Inability to weight-bear ... Fractures #msk #diagnosis ... #pathophysiology
Osgood-Schlatter Disease - MSK Radiology
Imaging Findings:
 • Infrapatellar fat-pad edema with loss of the patellar tendon
description: • Active ... exacerbated with activity ... tuberosity Differential diagnosis ... Patellar tendon tear ... clinical #Radiology #diagnosis
Low Ankle Sprain: Pathomechanics and Clinical Findings

Grading Ligament Sprains
l: Minimal ligament disruption, mild swelling & tenderness,
II: Incomplete tear ... Ill: Complete tear ... Grading #Grades #Diagnosis ... #pathophysiology
Osteoporosis: Pathogenesis and risk factors

 • Age > 30 (post-peak bone mass)
 • Post-menopausal women ->
smoking, etoh, decr activity ... #Osteoporosis #pathophysiology ... signs #symptoms #diagnosis
Rigors And Bacteremia - Overview

• Rigors are a response to the release of cytokines and prostaglandins
PATHOPHYSIOLOGY: ... vasculature via: • Active ... Rigors #Bacteremia #Pathophysiology ... #InfectiousDiseases ... #Diagnosis
Upper Versus Lower Motor Neuron Findings

Denervation near the target muscle fibers (lower motor neuron disease) results
Denervation near ... interpretation of proximal activity ... Versus #Findings #Diagnosis
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
Gaucher Disease Pathophsiology ... in macrophages Diagnosis ... ß-glucocerebrosidase activity ... Gauchers #Disease #Diagnosis