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management hepatology syndrome msk oncology rheumatology signs alkaline alp apml biliary cardiology carpal cholangitis cirrhosis comparison complications cryofibrinogenemia deficiency differential
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... ) Pathophysiology ... postpartum): • Initial symptoms ... = nonspecific (nausea ... AP, ↑INR, ↑BUN/Cr
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Most cases diagnosed ... • recurrent fractures ... collection with EDTA Pathophysiology ... mineralization Symptoms ... Phosphatase: • Other causes
Trendelenburg Gait: Pathogenesis and clinical findings Skeletal Pathology of the Hip • Arthritis • Congenital hip dysplasia
tears of gluteus medius ... Greater Trochanter Fracture ... Trendelenburg #Gait #pathophysiology ... #causes #symptoms ... #signs #diagnosis
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
without other cause ... ARDS to explain symptoms ... : Age>60, CKD, CHF ... fluid balance, and CXR ... #diagnosis #comparison
Iron Deficiency in Heart Failure Pathophysiology: Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Heart Failure Pathophysiology ... → Inflammation causes ... improvement in symptoms ... iron #deficiency #CHF ... #management #cardiology
Perilunate Dislocation On lateral wrist XR, the capitate ("apple") should sit in the lunate ("tea cup") which
lateral wrist XR ... styloid fracture ... repair MH/CCF ... Wrist #Carpal #Radiology ... #XRay #Diagnosis
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... , dyspnea, +/- CXR ... Syndrome #TLS #diagnosis ... #management #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... common • Imaging: CXR ... : >3 symptoms, or ... sepsis), PE, DAH, CHF ... #management #hematology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... intralobular bile ducts causes ... PBC Signs and Symptoms ... obstruction • ALP ... #workup #hepatology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Etiology: • Pathophysiology ... Neurological symptoms ... the brain • CSF ... the underlying cause ... with AEDs until cause
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