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diagnosis hematology algorithm generalized lad systemic diffuse focal hodgkins localized management pruritus secondary anemia anterior aplastic cellulitis chronic cll comparison
Causes of Diffuse and Localized Lymphadenopathy - Differential Diagnosis Algorithm • Reactive (Inflammatory / Infectious) •
Causes of Diffuse ... - Differential ... • Neoplastic (Leukemia ... , Lymphoma, Metastatic ... #Hematology #Oncology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Lymphadenopathy ... Non-Hodgkin's Lymphoma ... • Hodgkin's Lymphoma ... #Hematology #Oncology
Differential Diagnosis for Generalized Lymphadenopathy Viral • HIV • EBV • CMV • HBV • Dengue • Rubella
Differential Diagnosis ... Malignancy • Lymphoma ... • Leukemia • ... Diagnosis #Causes ... #Algorithm #Oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
Causes of Localized Lymphadenopathy - Differential Diagnosis Algorithm Cervical: - Anterior • Infection
Causes of Localized ... Lymphadenopathy ... - Differential ... •TB • Lymphoma ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Exam/Signs: • Lymphadenopathy ... • Richter’s Syndrome ... • Sezary syndrome ... diagnosis #workup #oncology ... #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
involved) • No leukemic ... translocation • Types: Classification ... disease: B symptoms, lymphadenopathy ... NonHodgkins #comparison #oncology ... #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Disorders - Differential ... (NHL) ~60% - lymphadenopathy ... Treated Like Acute Leukemias ... Lymphoproliferative #Disorders #Classification ... pathophysiology #Hematology
MIAMI Mnemonic for Differential Diagnosis of Lymphadenopathy Malignancies - Kaposi sarcoma, leukemias, lymphomas, metastases, skin neoplasms Infections -
Kaposi sarcoma, leukemias ... , lymphomas, metastases ... arthritis, Sjögren syndrome ... sarcoidosis Iatrogenic causes ... - Medications
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 Causes of Anterior Uveitis - Differential Diagnosis Anterior Uveitis - 90% of cases of Uveitis • Inflammation
Uveitis - Differential ... involvement) • Medication ... : Malignancy - Leukemia ... /Lymphoma Pearl ... Anterior #Uveitis #Differential
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