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anemia algorithm causes aflp classification deficiency hellp hepatology oncology pregnancy workup atlas cold extravascular hepatitis hodgkins intravascular liver lymphoma management
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Hemolytic Anemias ... - Differential ... of anemia and hemolysis ... Hemolytic Anemias ... #hematology
Anemia - Hemolysis Diagnostic Algorithm Autoimmune hemolytic anemia Microangiopathic hemolytic anemia Probable thalassemia Dr. Eric Strong @DrEricStrong - Strong Medicine
Anemia - Hemolysis ... Autoimmune hemolytic ... Microangiopathic hemolytic ... Anemia #Algorithm #hematology ... #diagnosis #differential
Warm vs Cold Autoimmune Hemolytic Anemia Warm Autoimmune Hemolytic Anemia: • Mechanism: IgG and Complement-mediated • Etiology:
Hemolytic Anemia ... Hemolytic Anemia ... Hemolytic Anemia ... #hematology #diagnosis ... #comparison
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
for Hemolysis - ... Intravascular Hemolysis ... Microangiopathic hemolytic ... purpura (TTP), Hemolytic ... #diagnosis #hematology
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table Warm AIHA (48-70%) Cold AHA (16-32%) • Donath-Landsteiner HA (paroxysmal
Autoimmune Hemolytic ... Diagnosis Table ... #Hemolytic #Anemia ... #Diagnosis #Table ... #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Intravascular Hemolysis ... and RES-mediated hemolysis ... Intravascular - Hemolysis ... immune-complex hemolytic ... #Causes #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... elliptocytosis, autoimmune ... hemolysis) ARUPConsult ... @ARUPLabs #Hemolytic ... #workup #hematology
Expected DAT Results in Autoimmune Hemolysis DAT Negative Hemolysis • DAT Poly ( - ), IgG (
Hemolysis DAT ... Negative Hemolysis ... Cold agglutinin disease ... #Hemolysis #hematology ... #diagnosis
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
-100): • Non-hemolytic ... anemia, CKD • Hemolytic ... - Extrinsic: Autoimmune ... Non-megaloblastic: Liver disease ... #Diagnosis #hematology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Diagnosis Congenital ... Diseases: • GATA2 ... Inflammatory and Autoimmune ... Antibody-mediated hemolysis ... #Diagnosis #Hematology
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