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diagnosis hematology causes treatment albumin blood product reactions saag aflp algorithm anemia apml atlas bleeding bruising cirrhosis coagulation dic differentiation
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... headache, malaise) → Acute ... develops (DIC, ascites ... infiltration) Differential ... #Pregnancy #hepatology
Indications for Albumin for Management of Cirrhosis • Large volume paracentesis (>5 liter) - 8g per
for Albumin for Management ... of ascites removed ... • Acute kidney ... #Indications #Management ... Cirrhosis #treatment #hepatology
Causes of Ascites - Differential Diagnosis Algorithm Portal Hypertension - Prehepatic: • Portal vein thrombosis • Splenic
- Differential ... Infiltrative disease • Acute ... liver failure ... #Differential # ... Diagnosis #Algorithm #Hepatology
Causes of Ascites Normal Peritoneum Portal hypertension (SAAG > 1.1 g/dL) 1. Hepatic congestionl
Liver disease ... fibrosis - Acute ... fatty liver of ... Causes #diagnosis #differential ... #hepatology #SAAG
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... of portal HTN: ascites ... portal HTN: • Ascites ... • Cirrhosis/acute ... Diagnosis #causes #hepatology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Megaloblastic anemia, Liver ... - Thalassemia, Liver ... Malignant tumors, Acute ... key #diagnosis #differential ... #hematology
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis High albumin gradient (>1.1 g/dl): - Cirrhosis - Alcoholic
Gradient (SAAG) - Differential ... - Massive liver ... Veno-occlusive disease - Acute ... fatty liver of ... #Diagnosis #hepatology
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
kidney disease, Acute ... : Alcohol use, Liver ... morphologic #mcv #differential ... diagnosis #causes #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... deficiency • Liver ... - APLS • Acute ... #Diagnosis #hematology ... #nonpalpable #dermatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Presentation: Subacute-Acute ... • Rare: DAH, acute ... initiation • Differential ... , Anaphylaxis, Acute ... #hematology #oncology
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