28 results
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
• Ischemic optic ... Neurologic system ... Genitourinary system ... Cardiovascular system ... differential #diagnosis #rheumatology
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Infection - Systemic ... Knee Effusions - Septic ... Seronegative Reactive Syndrome ... Ligamentous injuries - Meniscal ... Effusions: - Hematologic
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Clinical Presentation ... idiopathic arthritis ... brucellosis) • Sepsis ... #Diagnosis #Management ... #Hematology #Rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Systemic disease ... association • M > F Clinical ... erythema nodosum (septal ... (Clinical Dx). ... #diagnosis #management
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
likely it will be clinically ... Juvenile Idiopathic Arthritis ... SLE), Sjogren's Syndrome ... , Sjögren Syndrome ... ANA #patterns #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... Joints (90%): Aseptic ... of hip (rare), Arthritis ... Demyelinating syndromes ... pain (20%) Renal disease
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad ... Fever, Arthralgia/arthritis ... solid cancers • Systemic ... splenomegaly • Hepatic ... #diagnosis #management
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome ... Arthritis: • Colchicine ... #Syndrome #Treatment ... #management #pharmacology ... #rheumatology
Differential Diagnosis of Acute Arthritis

Crystal-induced arthritis: Calcium oxalate, gout, cholesterol, pseudogout, hydroxyapatite crystals

Infectious arthritis: Bacteria, fungi,
: Behçet syndrome ... erythematosus,* Still disease ... arthritis), systemic ... hyperlipoproteinemia,* meniscal ... Monoarticular #Septic
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
associated with systemic ... disease. ... Musculoskeletal system ... , breast CA - Hematologic ... erythema - Bacterial sepsis