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diagnosis rheumatology treatment lupus syndrome disease druginduced activation adultonset behcet cardiology causes coagulation comparison conditions constrictive cp differential disseminated echocardiogram
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
retinal exudates) - SLE ... • Ischemic optic ... infection • Still's ... Heberden's nodes (DIP ... differential #diagnosis #rheumatology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Disease Clinical ... Fever, Arthralgia/arthritis ... MAS, Visceral, DIC ... Disease #diagnosis #management
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Induced Lupus (DIL ... , Arthritis, myalgia ... rash is rare in DIL ... , SCLE-DIL (terbinafine ... for cutaneous DIL
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Intravascular Coagulation (DIC ... Manifestations of DIC ... Laboratory Findings in DIC ... MAHA: TTP/HUS > DIC ... for bleeding #DIC
Constrictive Pericarditis on POCUS Echocardiogram - Subcostal View Young Lupus patient admitted to hospital new onset HFpEF.
Pericarditis on POCUS ... What do you see ... Did have tap next ... echo findings still ... Echocardiogram #clinical
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 Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Oral aphthae : SLE ... : SLE, Reactive ... Syndrome #diagnosis #management ... #signs #symptoms ... #rheumatology #
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Induced Lupus (DIL ... to 1:1 F:M • Clinical ... , Arthritis, myalgia ... , SCLE-DIL (terbinafine ... diagnosis #treatment #management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Adult-onset Still ... erythematosus [SLE ... brucellosis) • Sepsis ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... , adult-onset Still ... lymphoproliferative syndrome Clinical ... , APLA, PAC • Aseptic ... Induced Lupus: • Symptoms
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... Autoimmune diseases: SLE ... +, Adult-onset Still ... Lymphohistiocytosis #diagnosis #management
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