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rheumatology differential dermatology management causes oncology signs symptoms table clinical algorithm classification cryoglobulinemic cutaneous erythematosus lupus monoclonal pulmonary sle arteritis
Diagnosis of Cryoglobulinemia Vasculitis 1) Presence of cryoglobulin Circulating immunoglobulins that precipitate with cold temperature and dissolve
Diagnosis of Cryoglobulinemia ... Vasculitis 1 ... Hyperviscosity syndrome ... #Vasculitis #Diagnosis ... #Rheumatology #
Small Vessel Vasculitides • Granulomatosis with polyangiitis - Granulomatous manifestations (e.g., nasal crusting, destructive sinusitis, pulmonary
involvement • Cryoglobulinemic ... and C viruses. systemic ... and Sjogren's syndrome ... in absence of skin ... #diagnosis
Non-HCV infectious mixed cryoglobulinemia vasculitis - Diagnosis, causes and management - French Vasculitis Study Group < 5%
vasculitis - Diagnosis ... vasculitis Clinical ... manifestations - Skin ... #Vasculitis #Rheumatology ... #Diagnosis #Management
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... - Purpura - Skin ... reticularis & skin ... Labs/Diagnosis: ... disorder (e.g. systemic
Renal involvement in 35% of mixed cryoglobulinemia vasculitis Associated with : • Absence of skin
vasculitis Associated ... • Absence of skin ... min/1.73 m2 at diagnosis ... • Dialysis at diagnosis ... #Rheumatology #
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
Diagnosis Framework ... Urticarial/LCV) - Cryoglobulinemic ... Disease • Cogan syndrome ... #skin #dermatology ... differential #diagnosis
Cutaneous Manifestations of Monoclonal Gammopathy • Extravascular lg Deposits: Systemic amyloidosis, Nodular amyloidosis, Macroglobulinoderma, Follicular hyperkeratotic
Extravascular lg Deposits: Systemic ... deposits: Type I cryoglobulinemia ... activity: Type II cryoglobulinemia ... manifestations #dermatology ... #skin #clinical
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... ANCA +MPO) • Cryoglobulinemic ... Vasculitis - Skin ... Low levels mixed cryoglobulinemia ... #rheumatology #
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Alpha & Mu) Skin ... thrombosis+Pulm HTN+skin ... (Cryoglobulinemic ... Paraproteinemias #Hematology ... #Differential #Diagnosis
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Differential Diagnosis ... Behcet disease, Cryoglobulinemia ... Immune Complex: Systemic ... Rheumatoid arthritis, Systemic ... #differential #diagnosis
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