23 results
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... Diagnosis Algorithm ... Rebound effect from treatment ... Inflammatory Conditions: Rheumatologic ... Vasculitides, IBD, Celiac disease
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
fraction < 20% Differential ... Diaqnoses: • ... Infectious: Mycoplasma ... #diagnosis #management ... #treatment #rheumatology
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
trauma (e.g., meniscal ... tears) • Congenital ... Joint #Pain #MSK #rheumatology ... approach #workup #differential ... #diagnosis #arthritis
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Knee Effusions - Differential ... Diagnosis Framework ... Ligamentous injuries - Meniscal ... Effusions #causes #differential ... #diagnosis #msk
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Autoimmune diseases ... Unknown cause Treatment ... Nicolas Taar ... #management #treatment ... #summary #rheumatology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Diagnosis Algorithm ... Myelofibrosis Infectious ... disorders • Celiac disease ... effect following treatment ... #Causes #Hematology
Differential Diagnosis of Acute Arthritis

Crystal-induced arthritis: Calcium oxalate, gout, cholesterol, pseudogout, hydroxyapatite crystals

Infectious arthritis: Bacteria, fungi,
Differential Diagnosis ... erythematosus,* Still disease ... hyperlipoproteinemia,* meniscal ... tear Systemic ... #Differential #
Ear Pain (Otalgia) - Differential Diagnosis Framework

Primary Otalgia 
 - Pain that originates from the ear
) - Differential ... Diagnosis Framework ... Previous episodes • Medical ... disease processes ... #diagnosis
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
incidentally during medical ... drug reaction, infection ... glucocorticoid treatment ... Disorders #Algorithm #Differential ... #diagnosis #hematology
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
Brain, Eye, and Ear ... and treatment can ... • Lyme disease ... noninflammatory #differential ... #diagnosis