21 results
hematology management syndrome workup aplastic chronic cll hemophagocytic hlh leukemia lymphocytic lymphohistiocytosis mds mgus monoclonal myelodysplastic symptoms acquired algorithm antinxp2
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
= funny-shaped cells ... cytopenias (usually anemia ... Allogeneic stem cell ... #Management #treatment ... #hematology #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Physical Exam/Signs ... • Neutropenia, anemia ... microglobulin Treatment ... #workup #oncology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Illness Script Signs ... Diagnosis: • Pancytopenia ... Treatment: • Consider ... stem cell transplant ... #treatment #hematology
Multiple Myeloma Diagnosis and Management Summary Clinical Signs: • hyperCalcemia 28% (bone demineralization) • Renal disease 48%
Management Summary Clinical ... Signs: • hyperCalcemia ... marrow plasma cells ... plasma clonal cell ... #Management #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
lymphocytes, smudge cells ... immunophenotype Clinical ... 5) Symptoms of anemia ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
40 ml/min A - Anemia ... marrow plasma cell ... • CML, B and T cell ... Gammopathies #MGUS #diagnosis ... #hematology #oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... Release from blast cells ... • Induce blast cell ... Renal Failure Treatment ... #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... number of CD34+ cells ... Treatment: ... #oncology #hematology ... #diagnosis #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
factor (GCSF) treatments ... marrow studies Treatment ... Immunosuppressive treatment ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... Etoposide/VP16 (100 mg ... #management #treatment ... #summary #rheumatology
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