27 results
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood ... Microangiopathic hemolytic ... DIC, TTP, HUS) ... #Peripheral #Blood ... Smear #Analysis #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... thrombocytopenia - DIC ... (oroya fever), babesia ... ARUPConsult @ARUPLabs #Hemolytic ... Algorithm #workup #hematology
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
Diagnosis for Hemolytic ... Bartonella, Babesia ... MAHA: TTP, HUS, DIC ... udaygulati #Hemolytic ... classification #hematology
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... microangiopathic hemolytic ... DIC is a clinical ... Microangiopathic hemolytic ... #anemia #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
etc) - Viral: HIV ... Parasitic: Malaria, babesia ... Microangiopathy: DIC ... Antibody-mediated: ITP, HITT ... Diagnosis #Framework #hematology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... MAHA: TTP, HUS, DIC ... - Peripheral Blood ... Urobilinogen #Hemolysis ... Differential #Diagnosis #hematology
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... spherocytosis, Hemolytic ... Schistocytes - Hemolytic ... coagulopathy (DIC ... #differential #hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
= (Retic %) x (Hct ... long (in days) it ... Retroperitoneal, Uterine • Hemolysis ... Microangiopathic hemolytic ... Production #Index #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
marrow disease - DIC ... /TTP/HUS - Hemolytic ... Coagulation Defects: • DIC ... necrosis) • VIT ... Purpura Fulminans (DIC
Spur-Cell Anemia- A 31-year-old man with a history of cirrhosis, recurrent hepatic encephalopathy, and anemia presented
..A peripheral-blood ... anemia, a form of hemolytic ... inflexible and prone to hemolysis ... anemia did not ... resolve despite blood