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diagnosis differential hepatology management causes treatment alkphos anemia arterial astalt atlas biliary bilirubin blood bloodcell chemistry cholangitis cirrhosis classification coagulation
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Diagnosis for Hemolytic ... Extrinsic Causes: • Liver ... warm, cold, drug induced ... Bartonella, Babesia ... classification #hematology
Drug-Induced Liver Injury - Pathophysiology Indirect Idiosyncratic Direct BWH Medicine Chiefs @BrighamChiefs #DILI #DrugInduced #Liver #Injury #Pathophysiology #hepatology
Drug-Induced Liver ... Injury - Pathophysiology ... #DrugInduced #Liver ... #Injury #Pathophysiology ... #hepatology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Microangiopathic Hemolytic ... Mechanical valve induced ... spherocytosis, Autoimmune hemolytic ... Cold autoimmune hemolytic ... differential #diagnosis #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Causes: - Drug induced ... DIC/TTP/HUS - Hemolytic ... deficiency • Liver ... Differential #Diagnosis #hematology ... #rheumatology #
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism AST and ALT: • AST: liver
Liver Chemistry ... In liver, 80% of ... synthesis, not reduced ... AlkPhos #Bilirubin #Hepatology ... #Pathophysiology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook Presentation: • Plts ↓50% (nadir
Heparin Induced ... ♀, ↑Age, ESRD Pathophysiology ... false ⊕’s, so use Bayesian ... #HIT #Heparin #Induced ... Management #Treatment #Hematology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... cholestasis → Cirrhosis/Liver ... or higher • Liver ... Sarcoidosis, Drug-induced ... diagnosis #workup #hepatology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
: • Leukocyte reduced ... RBC • Volume Reduced ... Hemolysis on labs ... eruptions, diarrhea, liver ... diagnosis #management #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Syndrome, Ischemic Liver ... Hyperhomocysteinemia - Heparin-induced ... Venous #Arterial #pathophysiology ... #hematology #differential
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
thrombin time • Reduced ... , V and II • Reduced ... protein C and S Pathophysiology ... DIC • Severe Liver ... treatment #management #hematology
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