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diagnosis differential hematology elevatedmcv macrocytosis mcv b12 bloodcell classification cobalamin hemolytic macrocytic management microcytic microscopy morphology nomenclature nutrition rbc red
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach ... Framework by MCV Microcytic ... Orotic aciduria, Drugs ... (e.g., hydroxyurea ... #MCV #Algorithm
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
RBC) Morphology Microcytic ... (sometimes) Macrocytic ... Chemotherapy (e.g ... disorders, Oxidative drugs ... hematology #microscopy #atlas
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Blood Smear • Drugs ... • Dietary Deficiency ... Increased Requirement (e.g ... #Causes #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Differential Diagnosis Algorithm ... Megakaryopoiesis • Aplastic Anemia ... • Folate Deficiency ... methotrexate) • Drugs
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
Differential Diagnosis Algorithm ... DAT (-) → G6PD Deficiency ... Hypochromic & microcytic ... autoimmune disease, drugs ... #causes
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Differential Diagnosis Algorithm ... Chronic Disease (e.g ... • Drugs • Reticulocytosis ... #Causes #Hematology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
Causes of Anemia ... Differential Diagnosis Algorithm ... RBC>13 • Iron Deficiency ... (Eg Causes: Chronic ... #Microcytic #Anemia
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
B12 (Cobalamin) Deficiency ... • Common Causes ... : • Worsening macrocytic ... , can consider IM ... B12 #Cobalamin #Deficiency
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