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differential hematology macrocytic microcytic elevatedmcv macrocytosis mcv normocytic atlas b12 classification cobalamin ddxof deficiency hemolytic honc im management microscopy morphology
Differential Diagnosis of Anemias #Diagnosis #IM #Honc #Anemia #Differential #Iron #Algorithm #Microcytic #Macrocytic #Normocytic #Ddxof
of Anemias #Diagnosis ... #IM #Honc #Anemia ... #Differential #Iron ... #Algorithm #Microcytic ... #Ddxof
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... Under 80 = microcytic ... of substrate (e.g ... . iron), low EPO ... #Algorithm #Diagnosis
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
, Thalassemia, Iron ... Chemotherapy (e.g ... disorders, Oxidative drugs ... Diseases #Red #BloodCell ... #differential #diagnosis
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach ... by MCV Microcytic ... inflammation) • Iron ... Orotic aciduria, Drugs ... (e.g., hydroxyurea
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
Causes of Anemia ... Algorithm Decreased ... (Eg Causes: Chronic ... #Microcytic #Anemia ... #Algorithm #Causes
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... Algorithm Decreased ... • Secondary (e.g ... • Early Iron ... #Algorithm #Causes
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... - Differential Diagnosis ... Algorithm Normal ... Blood Smear • Drugs ... #Algorithm #Causes
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
Algorithm Hereditary ... Hypochromic & microcytic ... RBCs, DAT (-) → ... autoimmune disease, drugs ... #Algorithm #causes
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Volume (<80 fL) • Iron ... Chronic Disease (e.g ... Deficiency • Drugs ... #Algorithm #Causes
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
• Common Causes ... : • Worsening macrocytic ... • Labs: - CBC ... , can consider IM ... consider other diagnosis
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