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diagnosis hematology differential obstetrics aflp aplastic common comparison cvid elevatedmcv fetal gestationalage growthrestriction hellp hemeonc hemophagocytic hlh hypogammaglobulinemia hypoxia immunodeficiency
Thrombocytopenia and Pregnancy Three syndromes in the critically ill pregnant woman who presents with coagulation defects. 1) HELLP
Thrombocytopenia ... Three syndromes ... child * Severe cases ... AFLP #Obstetrics #OBGyn ... #Hematology #Diagnosis
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Differential Diagnosis Algorithm ... Megakaryopoiesis • Aplastic Anemia ... Non-lmmune: • HELLP Syndrome ... #Causes #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Differential Diagnosis Algorithm ... Pregnancy) - Low ... Myelodysplastic Syndromes ... #Causes #Hematology
Factors that May Affect Fetal Oxygenation - Differential Diagnosis Algorithm Excessive Uterine Activity: • Hyperstimulation • Placental
Differential Diagnosis Algorithm ... • Post-dates pregnancy ... Antiphospholipid syndrome ... #Causes #Obstetrics ... #OBGyn
Causes of Intrauterine Growth Restriction / Small for Gestational Age - Differential Diagnosis Algorithm Fetal Factors: -
Causes of Intrauterine ... • Turner syndrome ... • Chronic anemia ... GrowthRestriction #Pregnancy ... #OBGyn
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... infections/fevers • Thrombocytopenia ... and petechiae Causes ... #oncology #hematology ... #diagnosis #management
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
specifically immune thrombocytopenia ... autoimmune hemolytic anemia ... DDX - Other causes ... : • Nephrotic syndrome ... (Epstein-Barr syndrome
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... caused by uncontrolled ... - Cytopenias (anemia ... , thrombocytopenia ... #Hematology #HemeOnc
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