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infectiousdiseases management differential treatment listeria listeriosis microbiology monocytogenes neurology 1 apml associated autoimmune cdi cdiff clostridioides clostridium cmv cns cytomegalovirus
Cytomegalovirus (CMV) in HIV-AIDS Patients Cytomegalovirus (CMV): double-stranded DNA virus, herpesvirus family. CMV infection: virus isolation or detection
Cytomegalovirus (CMV) in HIV-AIDS ... CMV infection: virus ... PCR and CMV pp65 ... Cardiovascular risk ... #AIDS #diagnosis
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
HIV / AIDS - Differential ... Diagnosis Framework ... cells per μL • Diagnosis ... #differential #diagnosis ... #AIDS #opportunistic
HIV-Associated Neurocognitive Disorder (HAND) Definition: HIV-Associated Neurocognitive disorders categories: • Asymptomatic neurocognitive impairment • Mild neurocognitive impairment • HIV dementia Pathophysiology: HIV frequently
dementia Pathophysiology ... early stages of infection ... • Depressive symptoms ... Diagnosis: MRI ... #AIDS #Neurology
Listeriosis Summary - Listeria Monocytogenes Pathogen: Listeria Monocytogenes - Gram-positive rod, Aerobic, facultative anaerobe, motile, beta-hemolytic, Non-spore-forming Risk
beta-hemolytic, Non-spore-forming ... Risk Factors: ... Diagnosis: ... Gastroenteritis) • PCR ... / CT if focal symptoms
Listeriosis Summary - Listeria Monocytogenes Pathogen: Listeria Monocytogenes - Gram-positive rod, Aerobic, facultative anaerobe, motile, beta-hemolytic, Non-spore-forming Risk
beta-hemolytic, Non-spore-forming ... Risk Factors: ... Diagnosis: ... Gastroenteritis) • PCR ... / CT if focal symptoms
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Attempt if high risk ... : >3 symptoms, or ... : Infection (sepsis ... • Steroids: IV ... fluid overload, PCC
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook Clinical Presentation + Progression:
Pathophysiology: Spore ... immunocompromised, IBD) • ↑Risk ... Lowest Risk: Tetracyclines ... non-toxigenic • Stool PCR ... Bezlotoxumab 10 mg/kg IV
Lung Infections in HIV - Differential Diagnosis Framework Disease by CD4 Count: Any CD4 Count: • Mycobacterium tuberculosis,
Lung Infections ... Diagnosis Framework ... Pneumonia: • Risk ... Constitutional symptoms ... #HIV #AIDS #pulmonary
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
Rheumatologic symptoms ... MUCORMYCOSIS • Risk ... Encapsulated yeast • At risk ... : AIDS, neutropenia ... transplantation • MCC
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
- Differential Diagnosis ... Tenderness → Consider infectious ... myopathies Diagnostic ... weakness + atrophy- Hip ... Other Diseases: • PBC
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