18 results
Leser–Trélat Sign on Physical Exam

Acute onset of multiple seborrheic keratoses, often a paraneoplastic sign of malignancy.

#Leser
PhysicalExam #clinical #video ... #skin #dermatology ... #oncology
Approach to the Rash in a an oncology patient - MINT-C Mnemonic
M - Malignancy: Leukemia cutis,
the Rash in a an oncology ... dermatoses #skin ... #Rash #oncology ... #differential # ... MINTC #Mnemonic #dermatology
Cutaneous manifestations associated with myelodysplastic syndrome
 • Myeloid hemopathy with the most frequent skin lesions (20%)
most frequent skin ... myelodysplastic #syndrome #differential ... #diagnosis #dermatology ... #oncology #clinical ... #skin
Erythroderma - Diagnostic Algorithm. Pathophysiology: 1) Extensive cutaneous capillary dilation, results in widespread exfoliation of the
Pathophysiology: ... of germinative skin ... Basophils/Histamine 4) Skin-homing ... #Diagnosis #Dermatology ... Nikolsky #Algorithm #Differential
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Diagnostic Algorithm Pathophysiology ... - Pathophysiology ... sulfa-drug - Skin ... #Diagnosis #Dermatology ... Targetoid #Algorithm #Differential
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... purple, hemorrhagic skin ... induced - Bone marrow ... Vasculopathy #Purpura #Differential ... #Diagnosis #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Hypocellular bone marrow ... Direct Damage to Marrow ... Headaches • Pale skin ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Hepatomegaly • Skin ... lymphocyte > 5000/microL ... AIHA • Bone marrow ... diagnosis #workup #oncology ... #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Arterial Thrombosis - Differential ... Testosterone - Coumadin skin ... Venous #Arterial #pathophysiology ... #hematology #differential
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... initiation • Differential ... diagnosis #management #hematology ... #oncology