21 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Diagnosis and Management ... • Bone marrow ... acute leukemia Management ... MDS #Diagnosis #Management ... #treatment #hematology
Suggested algorithm for bone marrow biopsy and skeletal imaging in patients with monoclonal gammopathy of undetermined
algorithm for bone marrow ... MGUS) A bone marrow ... algorithm #diagnosis #management ... #hematology #multiplemyeloma
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
hypocellular bone marrow ... Anemia #diagnosis #management ... #treatment #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Hypocellular bone marrow ... Direct Damage to Marrow ... MDS: • ↓ bone marrow ... Anemia #oncology #hematology ... #diagnosis #management
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Diagnosis and Management ... • Prognosis: Minor ... Usual therapeutic management ... Erythematosus #Diagnosis #Management ... #Summary #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
hemophagocytosis in the bone marrow ... staining of bone marrow ... found in the bone marrow ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Leukocytosis (10,000/microL ... Minor criteria include ... Leukocytosis (10,000/microL ... AOSD #diagnosis #rheumatology ... #management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Biological + Bone Marrow ... ↑ LDH • Bone marrow ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Progressive bore marrow ... Leukemia #oncology #hematology ... hemeonc #diagnosis #management
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
Diagnosis and Management ... Hypercellular bone marrow ... PV #Diagnosis #Management ... Summary #treatment #hematology