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diagnosis causes algorithm anemia coagulation abnormal aptt arthritis comparison disorders mcv oncology prolonged pt abscess antibodies approach associations atlas autoantibodies
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
Malabsorption (e.g ... warfarin, DOACs (e.g ... ) • Advanced Liver ... Autoimmune disorders (e.g ... comparison #diagnosis #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... Diagnosis and Workup ... : INR/PT, aPTT(liver ... function test, ANA (e.g ... #hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Volume (MCV) - Differential ... Chronic Disease (e.g ... Renal Disease, Liver ... Reticulocytosis • Liver ... Algorithm #Causes #Hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Approach to Anemia - Differential ... aciduria, Drugs (e.g ... Non-megaloblastic: Liver ... MCV #Algorithm #Differential ... #Diagnosis #hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Bleeding / Bruising - Differential ... Rare • Drugs (e.g ... Iatrogenic) • Liver ... Bleeding #Bruising #Differential ... Algorithm #Causes #Hematology
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Dermatomyositis Anti-LKM (liver ... - Vasculitis, e.g ... - Vasculitis, e.g ... diseases #diagnosis #table ... #rheumatology #
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Immunosuppression (e.g ... the spleen or liver ... Autoimmune diseases (e.g ... Malignancies (eg ... #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Volume (MCV) - Differential ... Increased Requirement (e.g ... Tests • Liver ... #elevatedMCV #Differential ... Algorithm #Causes #Hematology
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Pre-analytical cause (e.g ... inhibitory drugs (e.g ... specific inhibitor (e.g ... • Reduced liver ... #hematology #coagulation
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Folate deficiency, Liver ... Chemotherapy (e.g ... Artifact, Uremia, Liver ... RBC #Morphology #differential ... #diagnosis #hematology
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