204 results
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Induced Lupus vs SLE ... & NPSLE rare, Malar ... Manifestations: Malar ... are evocative of SLE ... druginduced #lupus #sle
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE ... Manifestations: Malar ... are evocative of SLE ... management of SLE ... Lupusreference #SLE
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
B19 infection Malar ... rash • SLE ... IBD • RA • SLE ... erythematosus • SLE
I’M DAMN SHARP - Lupus Diagnosis Mnemonic
I  	 Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid)
M 	 Malar Rash
D
Anti-phospholipid) M Malar ... #IMDAMNSHARP #sle
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
pattern: - SLE ... pattern: - SjS, SLE ... Speckled: - SLE ... anti-Su/Ago • Golgi/polar ... : - SLE, SjS
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework
Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis
90%:
 -
Diffuse alveolar hemorrhage ... Complement Levels: SLE ... infection/other hemorrhagic
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Arthritis 69% - Malar ... involvement 3% SLE-Related ... Lupusreference #SLE
Causes of Approach to Altered Level of Consciousness - Workup
Clinical Exam - Focal
 • Trauma
 •
• Tumor • Hemorrhage ... • See Imaging ... Abnormality • Epidural Hemorrhage ... • Subdural Hemorrhage ... • Intracranial Hemorrhage
Approach to Hemorrhagic Shock
PLAN FOR CONTROLLING HEMORRHAGE & ACTIVATE MASSIVE TRANSFUSION PROTOCOL
 • Activate massive transfusion
Approach to Hemorrhagic ... FOR CONTROLLING HEMORRHAGE ... Determine how hemorrhage ... resuscitation (see ... @nickmmark #Hemorrhagic
Infective Endocarditis - Diagnosis and Management Summary
Pearls:
 - Consider non-infectious endocarditis in pts with cancer/SLE and
pts with cancer/SLE ... lesions, splinter hemorrhages