15 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Pregnancy - TTP/HUS, HELLP ... coagulation defects. 1) HELLP ... AFLP #obstetrics #hematology ... #diagnosis #table ... #comparison
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Diagnosis Framework ... : Liver Injury ... Diagnosis: • ... NAFLD, Autoimmune, HELLP ... #Diagnosis #hepatology
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
coagulation defects. 1) HELLP ... Hemolysis, Elevated Liver ... Pregnancy #TTPHUS #HELLP ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Injury - Differential ... Diagnosis Hepatocellular ... biliary obstruction, HELLP ... #Injury #Differential ... #Diagnosis #Causes
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... - Differential Diagnosis ... • Pregnancy: HELLP ... disease: > 2 • NASH ... #differential #diagnosis
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver ... Injury Transaminase ... normal - Hemolysis, NASH ... #Injury #hepatology ... #differential #diagnosis
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
, no necrosis HELLP ... Disease #Pregnancy #hepatology ... obstetrics #hepatitis #comparison ... #differential #diagnosis ... #icp #HELLP #AFLP
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
injury < 26 weeks ... hepatocellular injury ... disease: > 2 • NASH ... #chemistry #diagnosis ... #differential #Hepatology
Monkeypox

What?
Monkeypox virus belongs to the family Poxviridae, subfamily Chordopoxvirinae, and genus orthopoxvirus
Viral zoonotic disease that is
Characteristic Rash ... • Fomites • Live ... Umbilification - Rash ... #MPOX #Diagnosis ... #Management #Dermatology
Hypertensive Disorders of Pregnancy
Chronic Hypertension:
 • Guidelines as SBP ≥130 or DBP ≥ 90 mmHg
 •
evidence of organ injury ... pits <100k), ↑ liver ... finding of organ injury ... preeclampsia patients • HELLP ... hemolysis, elevated liver