16 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
- TTP/HUS, HELLP ... coagulation defects. 1) HELLP ... AFLP #obstetrics #hematology ... #diagnosis #table ... #comparison
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
coagulation defects. 1) HELLP ... Hemolysis, Elevated Liver ... #TTPHUS #HELLP ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Injury - Differential ... Diagnosis Hepatocellular ... biliary obstruction, HELLP ... Toxic: Medication, Pregnancy ... Acute #algorithm #hepatology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
, no necrosis HELLP ... #hepatology #obstetrics ... #hepatitis #comparison ... #differential #diagnosis ... #icp #HELLP #AFLP
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Diagnosis Framework ... : Liver Injury ... Diagnosis: • ... NAFLD, Autoimmune, HELLP ... #Diagnosis #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... - Differential Diagnosis ... melanoma, myeloma • Pregnancy ... : HELLP • Iatrogenic ... #algorithm #hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... ) Differential Diagnosis ... Preeclampsia, HELLP ... #Pregnancy #hepatology ... obstetrics #obgyn #diagnosis
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... - Differential Diagnosis ... • Wilson's • Pregnancy ... - AFLP, HELLP ... Others #LFTs #Hepatology
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver ... Injury Transaminase ... normal - Hemolysis, NASH ... #Injury #hepatology ... #differential #diagnosis
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... - Differential Diagnosis ... AIH, Wilsons, Pregnancy ... - AFLP, HELLP ... #hepatology #LiverFunctionTests