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differential disease dermatology lupus sle symptoms syndrome treatment erythematosus pediatrics stills vasculitis adultonset aosd oncology table workup activation antinxp2 antinxp2dm
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
Systemic Sclerosis ... Scleroderma) Multi-system ... thickening Signs ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Arthralgia/arthritis, Skin ... solid cancers • Systemic ... #management #treatment ... #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features of Systemic ... Sjögrens (15%) Skin ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Diagnosis of IgA Vasculitis (Henoch-Schönlein Purpura) - French Vasculitis Study Group 1) Suggestive clinical manifestations
Diagnosis of IgA ... - Most common systemic ... years - Rare in adults ... #Rheumatology # ... Peds #Pediatrics
Behcet's Syndrome - Treatment Ulcers: • Treatment: Topical steroids • Prevention: Colchicine • Azathioprine for refractory disease Arthritis:
refractory disease Skin ... ophtho referral • Systemic ... Neuro disease: • Systemic ... Syndrome #Treatment #management ... #pharmacology #rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... Associated with skin ... #SLE #Summary #diagnosis ... #rheumatology # ... management
Combination of Skin Findings and Arthritis in Pediatrics Patient - Differential Diagnosis Malar rash: • A
- Differential Diagnosis ... migrans: • Target sign ... Suggestive of systemic ... #differential #diagnosis ... #peds #pediatrics
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
rendering the immune system ... Physical Exam/Signs ... Hepatomegaly • Skin ... ’s CLL Scoring system ... workup #oncology #hematology
Monkeypox What? Monkeypox virus belongs to the family Poxviridae, subfamily Chordopoxvirinae, and genus orthopoxvirus Viral zoonotic disease that is
both children and adults ... 28 days - Skin ... the onset of the systemic ... #MPOX #Diagnosis ... #Management #Dermatology
Adult-Onset Still's Disease (AOSD) Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's ... , difficult to diagnose ... episode (30%) Systemic ... Disease #AOSD #rheumatology ... #diagnosis #management
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