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symptoms sle differential erythematosus oncology summary arteritis arthritis behcet chronic classification cll comparison dermatology disease druginduced gca giantcell leukemia lymphocytic
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
Systemic Sclerosis ... thickening Signs ... Scleroderma #SSc #rheumatology ... #diagnosis #signs ... symptoms #testing #workup
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Lupus (SLE) General ... Sjögrens (15%) Skin ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... (SLE) - Diagnosis ... • Immunologic Workup ... #Diagnosis #Management ... #Summary #rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... Associated with skin ... #SLE #Summary #diagnosis ... #rheumatology # ... management
Combination of Skin Findings and Arthritis in Pediatrics Patient - Differential Diagnosis Malar rash: • A
- Differential Diagnosis ... migrans: • Target sign ... Suggestive of systemic ... #differential #diagnosis ... #peds #pediatrics
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... months to years) Systemic ... sle #comparison #table ... #rheumatology # ... diagnosis #management
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Alpha & Mu) Skin ... thrombosis+Pulm HTN+skin ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... #Differential #Diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... inflammation Others: • Lupus ... lupus erythematosus ... purpura: strong sign ... #rheumatology #
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
signs/sx of inflammation ... required due to skip ... them, but urgent rheumatology ... GCA #Temporal #Signs ... #Management
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
rendering the immune system ... Physical Exam/Signs ... Hepatomegaly • Skin ... #workup #oncology ... #hematology
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