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differential acute aki algorithm hematuria management workup kidneyinjury microscopy treatment urology acidosis acutekidneyinjury atlas cancer clinicopathology crisis crystals dipstick elevation
Acute Kidney Injury - Differential Diagnosis Framework PRERENAL: - Intrarenal vasoconstriction-hemodynamically mediated - Systemic vasodilation - Volume
Acute Kidney Injury ... cell casts on UA ... tubular cell casts ... or pigmented casts ... treating underlying cause
Atlas of Urine Microscopy Findings • Epithelial cells - Normal • Renal tubular cells - Acute
microscopy • Red cell casts ... • White cell casts ... • Hyaline casts ... disease • Granular casts ... #nephrology #casts
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... and Differential Diagnosis ... Investigations: full blood ... osmolarity If cause ... #nephrology #causes
Urinary Casts and Disease Associations Hyaline - May be nonspecific; seen in normal individuals or during severe
Urinary Casts and ... and concentrated urine ... breakdown of cellular casts ... heme-granular casts ... 34t5DgJ #Urinary #Casts
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
• 1ml blood/liter ... Immune mediated injury ... hematuria: - RBC casts ... #nephrology #renal ... #urine #blood
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm Acute Kidney Injury (AKI) - Acute increase
Kidney Injury (AKI ... - Differential Diagnosis ... Injury (AKI) - ... Epithelial cell casts ... #KidneyInjury #Nephrology
Causes of Acute Kidney Injury ( AKI ) - Prerenal, Renal, and Postrenal PRE-RENAL Impaired perfusion: •
Causes of Acute ... Kidney Injury ( ... • Sepsis • Blood ... /phimosis #Diagnosis ... #Differential #Nephrology
Hematuria Workup and Diagnosis Algorithm • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
Hematuria Workup and Diagnosis ... proteinuria, RBC casts ... for renal biopsy ... if cause not identified ... Workup #urology #blood
Simplified Approach to Acute Kidney Injury (AKI) 1) IS THIS AN EMERGENCY? Is there a dialysis indication
Approach to Acute Kidney ... Injury (AKI) 1 ... PROBLEM ~80% of AKI cases ... IMPROVEMENT If the urine ... for WBCs, RBCs, casts
Acute Kidney Injury - Classification Prerenal: • Dehydration • Heart failure (a.k.a. cardiorenal syndrome) • Liver failure
Acute Kidney Injury ... tubular necrosis (causes ... : sepsis, meds, ... #Injury #Classification ... #diagnosis #nephrology
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