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diagnosis lupus management dermatology sle erythematosus canimorsus dermatomyositis druginduced photo skin systemic treatment vasculitis adultonset antimda5 antimda5dm antinxp2 antinxp2dm autoimmune
Acute Purpura Fulminans Skin Rash on Physical Exam 60 year old male ITP s/p splenectomy 1d
Fulminans Skin Rash ... rigors, diarrhea, nausea ... new full-body rash ... can lead to the rash ... Fulminans #Skin #Rash
Capnocytophaga Canimorsus Skin Rash 40 M presents w/ N, V, severe epigastric pain. SHx: smoker, drinks 18
Skin Rash 40 ... Diffuse blanching rash ... dogs & latter can cause ... +purpuric rash → ... Canimorsus #Skin #Rash
Top 10 situations when to think about lupus 1) Inflammatory joint pain (especially in the wrists and
everywhere) 2) A rash ... the face (many differential ... 6) An annular rash ... 7) Always in case ... erythematosus #rheumatology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... arthritis, Skin rash ... fraction < 20% Differential ... management #treatment #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
40, F:M 9:1 • Clinical ... Manifestations: Malar rash ... Positive in 60-80% of cases ... Management #Summary #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... NPSLE rare, Malar rash ... 40, F:M 9:1 • Clinical ... Manifestations: Malar rash ... comparison #table #rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Rarely dominate the clinical ... Maculopapular rash ... reticularis Differential ... #dermatology #rash
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
(blue-purple) rash ... • Erythematous rash ... auricular papules Clinical ... Men • ~50% of cases ... Dermatomyositis #rheumatology
Capnocytophaga GNR with long fusiform shape. Fastidious facultative anaerobe that grows slowly and needs enriched agar C.
Capnocytophaga GNR ... = most common cause ... cats) Classic clinical ... shock with fever, rash ... InfectiousDiseases #Capnocytophaga
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
evidence of (fatigue, rash ... eruption - Butterfly rash ... Photosensitive rash ... permanent alopecia Differential ... Photosensitivity • Malar rash
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