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diagnosis management erythematosus vasculitis classification differential druginduced photo syndrome treatment activation adultonset canimorsus clues comparison cryoglobulinemia cryoglobulins dermatology disease fulminans
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... 40, F:M 9:1 • Clinical ... Manifestations: Malar rash ... versus DIL • ... #lupus #Systemic
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Lupus (DIL): ... NPSLE rare, Malar rash ... SCLE-DIL (terbinafine ... Manifestations: Malar rash ... #table #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... of Systemic Lupus ... Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... #SLE #systemic
Acute Purpura Fulminans Skin Rash on Physical Exam 60 year old male ITP s/p splenectomy 1d
Rash on Physical ... new full-body rash ... can lead to the rash ... shock, multiorgan system ... #Rash #clinical
Capnocytophaga Canimorsus Skin Rash 40 M presents w/ N, V, severe epigastric pain. SHx: smoker, drinks 18
Skin Rash 40 ... air conditioning system ... Diffuse blanching rash ... +purpuric rash → ... #Rash #dermatology
Top 10 situations when to think about lupus 1) Inflammatory joint pain (especially in the wrists and
everywhere) 2) A rash ... 6) An annular rash ... #diagnosis #sle ... #clues #system ... erythematosus #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... evidence of (fatigue, rash ... eruption - Butterfly rash ... Photosensitive rash ... #Systemic #Lupus
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
lupus erythematosus ... Petechial or purpuric rash ... lupus erythematosus ... [SLE], AOSD) • ... #Rheumatology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... Arthralgia/arthritis, Skin ... rash ± odynophagia ... solid cancers • Systemic ... management #treatment #rheumatology
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
to 1:1 F:M • Clinical ... NPSLE rare, Malar rash ... SCLE-DIL (terbinafine ... Discontinuation of causal ... #DIL #rheumatology
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