17 results
Hyperkalemia Differential Diagnosis Algorithm
R/O Pseudo-hyperkalemia:
 • Possible Lab error! Alwavs Repeat Blood sample!
 • Leukocytosis, Thrombocytosis:
TTKG should be high ... to excrete more K+ ... reduce plasma [K+ ... Diagnosis #Algorithm #causes ... #potassium #high
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
phlebotomy High ... Burns • Trauma/Crush ... • Recent IV potassium ... differential #diagnosis #causes ... #potassium #high
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
phlebotomy High ... Burns • Trauma/Crush ... • Recent IV potassium ... differential #diagnosis #causes ... #potassium #high
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
treated with IV potassium ... wasting from other causes ... suggests extra-renal causes ... urinary losses: • High ... #differential #potassium
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Pathophysiology 1) Na/K ... action of the Na+/K+ ... blocks the Na+/K+ ... intracellular calcium causes ... Hyperkalemia (high
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... constipation, diarrhea, nausea ... hypokalemia); nausea ... patients sensitive to high ... of aspiration #Potassium
Salicylate Toxicity - Diagnosis and Management

Consider if:
1) Patient is hot and altered
2) You see tachypnea with
no respiratory cause ... exposure Symptoms: Nausea ... Respiratory Alkalosis, High ... Lactate, Low Potassium ... 4.5 mmol/L 4) K
Hyperkalemia Management Algorithm
 • Treat the cause & optimize hemodynamics and ventilation
 • Reconsider treatment leadingto
• Treat the cause ... and parenteral potassium ... Intracellular K+ ... Shift 3) K+ Excretion ... #high
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Weakness, cramping, nausea ... Lysis (TLS, rhabdo/crush ... tourniquet / IVF line draw ... only if no clear cause ... Management #Treatment #potassium
Causes of Hyperkalemia - Differential Diagnosis Framework
 • Cellular Shift:
   - Exercise
Causes of Hyperkalemia ... to Aldosterone: K ... production: TLS, Crush ... hyperkalemia: Blood draw ... #potassium #high