23 results
Childhood Immunization Schedule: Why we immunize
 • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
cause quadriplegia ... & hemorrhagic rash ... Maternal viremia causes ... Vesicular & pruritic rash ... peds #pediatrics #pathophysiology
Hyperuricemia: Pathogenesis and Complications

 - Hypercalcemia (due to diseases like Sarcoidosis and Hyperparathyroidism) -> Accumulation of
blood - Tubular Poisons ... keto-acids) -> Poisons ... Release of purine bases ... Hyperuricemia #Pathophysiology
Erythema Ab Igne on Physical Exam

Erythema ab igne (EAI) is a skin reaction caused by chronic
Erythema Ab Igne ... Exam Erythema ab ... skin reaction caused ... #Igne #AbIgne #PhysicalExam ... #dermatology #rash
Erythroderma - Diagnostic Algorithm. Pathophysiology: 1) Extensive cutaneous capillary dilation, results in widespread exfoliation of the
Pathophysiology: ... Causes: 1) Exfoliative ... #Dermatology #Rash
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Rash - Differential ... : • Palpable Rash ... Diagnosis #Algorithm #Causes ... #dermatology #physicalexam
Erythemas Summarized
Erythema ab igne
 • A dermatosis that results from repeated exposure to heat (fires, heating
Summarized Erythema ab ... potential inciting causes ... Haverhill fever caused ... with variety of causes ... • Cause is unknown
Anaplasma Infection - Anaplasma phagocytophilum
Pathophysiology: 
 • Obligate, intracellular bacteria
 • Transmitted via blacklegged tick —
phagocytophilum Pathophysiology ... shaking chills • Rash ... is rare (< 10% cases ... ), cough (30% cases
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
reaction -> Benign Rash ... Systemic effect -> Nausea ... hyponatremia, rash ... #SideEffects #Pathophysiology
Leg Pain - Differential Diagnosis Framework

Bone/Joint Causes of Leg Pain:
 • Fracture
 • Arthritis
 • Gout/pseudogout
Bone/Joint Causes ... Hematoma Venous Causes ... • Trauma • Crush ... blunt trauma, crush ... extremity #msk #physicalexam
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
hair follicles -> causes ... plugging -> Discoid Rash ... Malar (butterfly) Rash ... Manifestations #pathophysiology