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diagnosis differential management manifestations rheumatology vasculitis allergy anaphylaxis anaplasma bells classification cns complications cord coronavirus covid19 disorders encephalitis extrapulmonary geography
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
hair follicles -> causes ... plugging -> Discoid Rash ... Malar (butterfly) Rash ... #diagnosis #signs ... #symptoms #complications
Anaplasma Infection - Anaplasma phagocytophilum Pathophysiology: • Obligate, intracellular bacteria • Transmitted via blacklegged tick —
phagocytophilum Pathophysiology ... within morulae Signs ... and symptoms: ... shaking chills • Rash ... ), cough (30% cases
Extrapulmonary manifestations of COVID-19 • Neurologic: Headaches, Dizziness, Encephalopathy, Guillain-Barré, Ageusia, Myalgia, Anosmia, Stroke • Renal:
of COVID-19 • Neurologic ... Gastrointestinal: Diarrhea, Nausea ... , Erythematous rash ... Extrapulmonary #Diagnosis #Signs ... #Symptoms #SARSCOV2
Manifestations of Anaphylaxis by Body System Dermatologic/mucosal - Eyes: periorbital swelling/erythema, injected conjunctiva, tears - Oral mucosa:
Skin: urticarial rash ... , morbilliform rash ... abdominal cramps Neurologic ... Diagnosis #Allergy #Signs ... #Symptoms #Anaphylaxis
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 CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework Viral Encephalitis: MCC: Enteroviruses (e.g., coxsackievirus
Coltivirus Symptoms ... Maculopapular rash ... Acute meningeal signs ... • Uveitis • Rash ... differential #diagnosis #neurology
Bell's Palsy - Diagnosis and Management Summary - GrepMed Handbook Acute Idiopathic Unilateral Facial Nerve (CN7) Palsy Presentation:
ophthalmoplegia), systemic signs ... (rash, swelling ... Imaging (if atypical symptoms ... CNS inflammatory cause ... Management #Treatment #Neurology
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
and signs below ... Non-compressive Spinal Cord Causes ... Behcet disease - SLE ... disorders #diagnosis #neurology ... differential #algorithm
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework Heat Cramps: • Muscle pain or spasm -
fatigue Heat Rash ... Collapse: • Pathophysiology ... → Syncope • Signs ... /Symptoms: - Lightheadedness ... differential #diagnosis #causes
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... • Bilateral signs ... and/or symptoms ... Disorders: - SLE ... diagnosis #management #neurology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... purpura: Strong sign ... , mucositis • Rash ... • Progressive symptoms ... tract, and often causes
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