23 results
diagnosis differential causes hematology management pulmonary autoimmune extravascular hemolysis hypertension intravascular phtn secondary types warm workup abnormalities agglutinin aiha approach
Warm vs Cold Autoimmune Hemolytic Anemia Warm Autoimmune Hemolytic Anemia: • Mechanism: IgG and Complement-mediated • Etiology:
Warm vs Cold Autoimmune ... Hemolytic Anemia ... Lymphoproliferative disorder ... , Autoimmune disorder ... BostonChiefs #Warm #Cold
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
anemia): ... Autoimmune (AIHA)"Cold ... (e.g. primary cold ... lymphoproliferative disorders ... diagnosis #hematology #anemia
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
lymphoproliferative disorder ... infection, autoimmune disorder ... • Symptoms of anemia ... anemia • Cold ... #anemia #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Differential Diagnosis Algorithm ... Warm AIHA • Cold ... Complement-Mediated • Cold ... anemia • ... Differential #Diagnosis #Algorithm
Shock Classification Shock Definition: State of cellular and tissue hypoxia due to: reduced oxygen delivery, increased oxygen
Shock Classification ... end-organ damage, multisystem ... CARDIOGENIC (Cold ... OBSTRUCTIVE (Cold ... #Classification
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Differential Diagnosis Algorithm ... Agglutination - Cold ... Consider RBC membrane disorder ... #Anemia #Differential
Shock Types - Classification State of cellular and tissue hypoxia due to: reduced oxygen delivery, increased oxygen
Shock Types - Classification ... tachycardia, dyspnea, cold ... end-organ damage, multisystem ... ring OBSTRUCTIVE (Cold ... #Classification
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Microangiopathic Hemolytic ... Unstable hemoglobin disorders ... Cell Agglutinate: Cold ... autoimmune hemolytic ... cold hemoglobinuria
Pulmonary Function Tests (PFTs) - Interpretation Algorithm • Normal • Pulmonary Hypertension, Anemia, Carboxyhemoglobinemia • Chest
Interpretation Algorithm ... Hypertension, Anemia ... Neuromuscular Disorders ... Emphysematous COPD ... Interpretation #Algorithm
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Diagnosis for Hemolytic ... Anemia Intrinsic ... • AIHA: warm, cold ... #Anemia #Differential ... Diagnosis #causes #classification
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