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causes hepatology nephrology algorithm aki transaminitis blood classification gastroenterology kidney pharmacology renal workup acidosis aclf acutekidneyinjury anesthesia anesthesiology checklist chemistry
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Tests (LFTs) - ... Differential Diagnosis ... Hepatopathy • Acute ... • DILI (Drug-induced ... liver injury)
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Liver Injury (DILI ... Chronic - ongoing ↑ LFTs ... #Liver #Injury ... #Diagnosis #Management
Causes of Severe Acute Liver Injury - Ichemic hepatitis - Acute biliary obstruction - Drug-Induced liver
Liver Injury ... obstruction - Drug-Induced ... liver injury ... #Causes #Differential ... #Hepatology #Diagnosis
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... nucleotidase (5-NT ... #chemistry #diagnosis ... #differential # ... transaminitis #LFTs
Acute Kidney Injury (AKI) - Differential Diagnosis Framework PRE-Renal AKI: • Hypovolemia • Congestion • Medications •
Acute Kidney Injury ... (AKI) - Differential ... Diagnosis Framework ... Infection-mediated, Drug-induced ... Diagnosis #nephrology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... - Differential ... Diagnosis Algorithm ... Liver Injury: ... #differential #
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... > 20x normal - Acute ... #LFTs #transaminitis ... #differential # ... diagnosis
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... Hepatitis (AAH) Drug-Induced ... Liver Injury (DILI ... gastroenterology #management ... #diagnosis
Vancomycin Associated Acute Kidney Injury • Drug induced acute kidney injury is generally defined as a
Vancomycin Associated Acute ... • Drug induced ... acute kidney injury ... pharmacology #toxicology #diagnosis ... #management #nephrology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... Diagnosis Baseline ... troponin, CK-MB, NT-proBNP ... #Kidney #Injury ... #Diagnosis #nephrology
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