12 results
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
Nephritic vs Nephrotic ... the patient have glomerular ... hematuria (RBC ... #Nephritic #Nephrotic ... Comparison #Algorithm #Nephrology
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
Glomerular Diseases ... - Nephritic and ... RBC casts in urine ... diabetes)) #Glomerular ... #Proteinuria #Nephrology
Causes of Hematuria - Differential Diagnosis Algorithm
Red blood cells on urine microscopy. Must exclude false positives
cells on urine microscopy ... Dysmorphic RBCs and/or RBC ... • Hereditary nephritis ... with polyangiitis/microscopic ... and >3.5g/day (nephrotic
Summary of characteristic abnormalities of selected glomerular diseases
Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
abnormalities of selected glomerular ... EM) Haematuria/nephritis ... Haemolytic-uraemic syndrome Nephrotic ... polyangiitis #glomerular ... #diseases #nephrology
Atlas of Urine Microscopy Findings
 • Epithelial cells - Normal
 • Renal tubular cells - Acute
Atlas of Urine Microscopy ... red - cells Non-glomerular ... Diagnostic of glomerular ... brown cast” - Necrotic ... key #diagnosis #nephrology
Algorithmic Approach to Acute Interstitial Nephritis
When to suspect AIN? (not sensitive)
 • AKI, AKD, rapidly progressive
Acute Interstitial Nephritis ... sterile pyuria, WBC ... eosinophiluria, microscopic ... #Interstitial #Nephritis ... AIN #Algorithm #nephrology
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
urine sediment Microscopic ... urine sediment by microscopy ... or dipstick) Glomerular ... • Causes of Glomerular ... causes #urology #nephrology
Urine Microscopy - Casts
Acellular Casts
 • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... suggestive of nephrotic ... glomerulonephritis • WBC ... #Casts #Urine #Microscopy ... #nephrology #interpretation
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
• Drugs Glomerular ... urine sediment - WBC ... /RBC casts ... polyangiitis (GPA) / microscopic ... #Proteinuria #Nephrology
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN
 • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
Sediment (dysmorphic RBC ... , RBC casts, +/- ... formation along glomerular ... glomerulopathy, radiation nephritis ... Glomerulonephritis #MPGN #nephrology