25 results
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
Nephritic vs Nephrotic ... the patient have glomerular ... RBCs in urine)? ... Comparison #Algorithm #Nephrology ... #Diagnosis
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
- Nephritic and ... Nephrotic Syndromes ... RBC casts in urine ... #Proteinuria #Nephrology ... #Diagnosis
Causes of Hematuria - Differential Diagnosis Algorithm
Red blood cells on urine microscopy. Must exclude false positives
Algorithm Red blood ... cells on urine ... microscopy. ... • Hereditary nephritis ... and >3.5g/day (nephrotic
Urinary Casts and Disease Associations
Hyaline - May be nonspecific; seen in normal individuals or during severe
and concentrated urine ... are seen in acute ... tubulointerstitial nephritis ... tuberculosis Fatty - Nephrotic ... #Diagnosis #Nephrology
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
- Differential Diagnosis ... • 1ml blood/liter ... castsDiagnostic ... #nephrology #renal ... #urine #blood
Lupus Nephritis - Diagnostic approach to kidney disease associated with systemic lupus erythematosus (SLE)
SLE patient develops
Lupus Nephritis ... > 500 mg/d • Nephritic ... urine sediment ... casts, WBC casts ... 5%) #Lupus #Nephritis
Urine Microscopy - Casts
Acellular Casts
 • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... suggestive of nephrotic ... glomerulonephritis • WBC ... #Urine #Microscopy ... #diagnosis
Algorithmic Approach to Acute Interstitial Nephritis
When to suspect AIN? (not sensitive)
 • AKI, AKD, rapidly progressive
Interstitial Nephritis ... sterile pyuria, WBC ... , microscopic hematuria ... #Interstitial #Nephritis ... #diagnosis
Hematuria Workup and Diagnosis Algorithm
 • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
repeat testing • Acute ... WBCs, or urine ... • Evidence of glomerular ... if cause not identified ... Workup #urology #blood
Atlas of Urine Microscopy Findings
 • Epithelial cells - Normal
 • Renal tubular cells - Acute
Atlas of Urine Microscopy ... tubular cells - Acute ... - Diagnostic of ... brown cast” - Necrotic ... #nephrology #casts