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differential algorithm acute hematuria hyponatremia kidneyinjury proteinuria urine classification glomerulonephritis injury kidney management syndromes urology workup ain associated atlas blood
Nephritic vs Nephrotic Syndrome Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes. Step
/nephritic syndromes ... the patient have glomerular ... casts or dysmorphic ... #Algorithm #Nephrology ... #Diagnosis
Glomerular Diseases - Nephritic and Nephrotic Syndromes Nephritic syndrome—due to GBM disruption. Hypertension. t BUN and creatinine.
Nephrotic Syndromes ... Nephritic syndrome—due ... RBC casts in urine ... but in severe cases ... #Nephrotic #Syndromes
Algorithmic Approach to Acute Interstitial Nephritis When to suspect AIN? (not sensitive) • AKI, AKD, rapidly progressive
Acute Interstitial Nephritis ... casts, eosinophiluria ... proteinuria, granular casts ... #Interstitial #Nephritis ... #diagnosis
Urinary Casts and Disease Associations Hyaline - May be nonspecific; seen in normal individuals or during severe
Urinary Casts and ... heme-granular casts ... tubulointerstitial nephritis ... Fatty - Nephrotic ... #Diagnosis #Nephrology
Urine Microscopy - Casts Acellular Casts • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
suggestive of nephrotic ... • RBC Casts - ... glomerulonephritis • WBC ... #nephrology #interpretation ... #diagnosis
Causes of Hematuria - Differential Diagnosis Algorithm Red blood cells on urine microscopy. Must exclude false positives
- Differential Diagnosis ... cells on urine microscopy ... casts) - Isolated ... • Hereditary nephritis ... and >3.5g/day (nephrotic
Atlas of Urine Microscopy Findings • Epithelial cells - Normal • Renal tubular cells - Acute
• Red cell casts ... • White cell casts ... • Hyaline casts ... disease • Granular casts ... #nephrology #casts
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
- Differential Diagnosis ... disease - Alport syndrome ... pain hematuria syndrome ... casts → Diagnostic ... #nephrology #renal
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm Acute Kidney Injury (AKI) - Acute increase
• Hepatorenal syndromes ... Epithelial cell casts ... polyangiitis /microscopic ... Acute Interstitial Nephritis ... #KidneyInjury #Nephrology
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
, RBC casts, +/- ... formation along glomerular ... anti-phospholipid syndrome ... glomerulopathy, radiation nephritis ... #diagnosis #renal
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