12 results
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
hematuria and/or proteinuria ... /nephritic syndromes ... casts or dysmorphic ... RBCs in urine)? ... #Diagnosis
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
Nephrotic Syndromes ... RBC casts in urine ... severe cases ... #Nephrotic #Syndromes ... #Nephrology #Diagnosis
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... • Fanconi's syndrome ... • Drugs Glomerular ... RBC casts ... #Nephrology #Differential
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
- Differential Diagnosis ... syndrome: • ... castsDiagnostic ... - Proteinuria ... #nephrology #renal
Algorithmic Approach to Acute Interstitial Nephritis
When to suspect AIN? (not sensitive)
 • AKI, AKD, rapidly progressive
Acute Interstitial Nephritis ... casts, eosinophiluria ... , granular casts ... #Interstitial #Nephritis ... #nephrology #diagnosis
Urine Microscopy - Casts
Acellular Casts
 • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... suggestive of nephrotic ... • RBC Casts - ... #Urine #Microscopy ... #nephrology #interpretation
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN
 • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
Mesangiocapillary GN ... • Active Urine ... , RBC casts, +/- ... glomerulopathy, radiation nephritis ... #diagnosis #renal
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
cell/white cell casts ... In each diagnosis ... because nephritic ... #glomerular #proteinuria ... #nephrotic #syndrome
Staphylococcus-associated GlomeruloNephritis - Diagnosis and Management Summary
CLINICAL
 • Nephritic syndrome (Casts)
 • Marked proteinuria (may be
CLINICAL • Nephritic ... syndrome (Casts ... ) • Marked proteinuria ... (may be nephrotic ... GlomeruloNephritis #nephrology
Urinary Casts and Disease Associations
Hyaline - May be nonspecific; seen in normal individuals or during severe
Urinary Casts and ... heme-granular casts ... tubulointerstitial nephritis ... Fatty - Nephrotic ... #Diagnosis #Nephrology