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differential algorithm aki hematuria workup blood kidneyinjury proteinuria syndrome syndromes urology acutekidneyinjury atlas classification comparison diseases diuresis diuretics excretion glomerulonephritis
Nephritic vs Nephrotic Syndrome Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes. Step
the patient have glomerular ... casts or dysmorphic ... RBCs in urine)? ... Comparison #Algorithm #Nephrology ... #Diagnosis
Glomerular Diseases - Nephritic and Nephrotic Syndromes Nephritic syndrome—due to GBM disruption. Hypertension. t BUN and creatinine.
RBC casts in urine ... severe cases ... may be in nephrotic ... #Proteinuria #Nephrology ... #Diagnosis
Atlas of Urine Microscopy Findings • Epithelial cells - Normal • Renal tubular cells - Acute
Atlas of Urine Microscopy ... • Red cell casts ... • White cell casts ... • Hyaline casts ... #nephrology #casts
Urine Microscopy - Casts Acellular Casts • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... suggestive of nephrotic ... • RBC Casts - ... #Urine #Microscopy ... #diagnosis
Urinary Casts and Disease Associations Hyaline - May be nonspecific; seen in normal individuals or during severe
Urinary Casts and ... are seen in acute ... tubulointerstitial nephritis ... Fatty - Nephrotic ... #Diagnosis #Nephrology
Causes of Hematuria - Differential Diagnosis Algorithm Red blood cells on urine microscopy. Must exclude false positives
blood cells on urine ... microscopy. ... casts) - Isolated ... • Hereditary nephritis ... and >3.5g/day (nephrotic
Algorithmic Approach to Acute Interstitial Nephritis When to suspect AIN? (not sensitive) • AKI, AKD, rapidly progressive
Interstitial Nephritis ... casts, eosinophiluria ... proteinuria, granular casts ... #Interstitial #Nephritis ... #nephrology #diagnosis
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
- Differential Diagnosis ... syndrome: • Flank pain ... casts → Diagnostic ... #Differential #Diagnosis ... #nephrology #renal
Hematuria Workup and Diagnosis Algorithm • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
repeat testing • Acute ... WBCs, or urine ... • Evidence of glomerular ... casts, dysmorphic ... for renal biopsy
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm Acute Kidney Injury (AKI) - Acute increase
Causes of Acute ... Epithelial cell casts ... polyangiitis /microscopic ... Interstitial Nephritis ... #KidneyInjury #Nephrology
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