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algorithm hemolysis intravascular management agglutinin classification cold disease hodgkins lymphoma neutropenia oncology platelets thrombocytosis thromboticthrombocytopenicpurpura ttp warm workup
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Warm Antibody Autoimmune ... Hemolytic Anemia ... #Autoimmune #Hemolytic ... #Anemia #diagnosis ... #rheumatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... anemia): ... #Causes #differential ... #diagnosis #hematology ... #anemia
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... Hemolysis - Differential ... anemia • ... Differential #Diagnosis ... #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Approach to Thrombocytosis ... Peripheral Smear ... → Refer to hematology ... , deficiency anemia ... #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
result in severe anemia ... Peripheral blood smear ... anemia Indirect ... WBC count and differential ... #Workup #Hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
• Symptoms of anemia ... Diagnosis: • hemolytic ... anemia • Cold ... IgM) • Blood smear ... #anemia #hematology
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
hypertension and/or drug treatment ... - Maternal antibody ... Megaloblastic anemia-rare ... #diagnosis #causes ... #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... Weight loss • Anemia ... nodosum • Immune hemolytic ... anemia • Pain ... classification #hematology
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