40 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... Neutrophils • Immature/Myeloblasts ... - infiltrates (anemia ... Leukemia #Hematology #Oncology ... #Diagnosis
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
cytopenias (usually anemia ... Allogeneic stem cell ... Myelodysplastic #Syndrome #MDS ... #Diagnosis #Management ... #oncology
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... , MDS, Chemotherapy ... , McLeod blood group ... RBC #Morphology #differential ... #diagnosis #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Diagnosis: • ... cells can indicate disease ... Lymphocytosis: Absolute blood ... microglobulin Treatment ... #workup #oncology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
cell count (anemia ... Myeloproliferative Disease ... differential • ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
of peripheral blood ... on the left Myeloblast ... • Autoimmune diseases ... cultures, including blood ... #differential #
Hepatobiliary Manifestations of Sickle Cell Disease
Acute sickle cell hepatic crisis:
 • Fever, acute onset RUQ pain,
Disease Acute ... Supportive with treatment ... Supportive with blood ... hepatology #hepatitis #differential ... #diagnosis
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
minimal tumor burden Diagnosis ... chemotherapy for low-risk disease ... Lauren Banaszak, MD ... Lymphocytic #Leukemia #oncology ... #management
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... Infection exposure (l MD ... plateletcount), peripheral blood ... (CVID, WAS), (neurologic ... not required in all
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
hematology for workup ... hematologic: Acute blood ... Rebound effect from treatment ... Vasculitides, IBD, Celiac disease ... Matthew Ho, MD