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differential anemia causes hemolysis oncology chronic cll lymphocytic management classification extravascular hemeonc hodgkins intravascular lymphoma macrocytic mcv microcytic neutrophil normocytic
Hemolytic Anemia - Hemolysis Diagnostic Workup Infographic by: Howard Ong #Hemolysis #Hemolytic #Anemia #Algorithm #MAHA #TTP #Diagnosis #Workup
Hemolytic Anemia ... #Hemolytic #Anemia ... #Algorithm #MAHA ... #TTP #Diagnosis ... #Workup #Hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
- Differential Diagnosis ... anemia • ... Shearing • MAHA ... (TTP, DIC, HUS) ... #Hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... Algorithm Decreased ... Anemias (MAHA) ... #Normocytic #Anemia ... #Hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
to Anemia - Differential ... Sideroblastic anemia ... ACD, Aplastic anemia ... Extrinsic: Autoimmune, MAHA ... #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... aHUS, mechanical cardiac ... #Anemia #Differential ... #Diagnosis #Algorithm ... #workup #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Algorithm Spurious ... Artifact (redo CBC ... Chronic Myelogenous Leukemia ... Iron deficiency anemia ... #Hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Diagnosis Framework ... Fragmentation - MAHA ... : TTP, HUS, DIC, ... Defects: Sickle cell anemia ... #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... result in severe anemia ... anemia Indirect ... from ischemia WBC ... #Workup #Hematology
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Bandemia Overview ... on the left Myeloblast ... Tissue damage • Leukemia ... Degree of bandemia ... #CBC #hematology
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... for degree of anemia ... thecurbsiders podcast #Anemia ... #Algorithm #Diagnosis ... #Workup #Hematology
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