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hematology algorithm oncology elevatedmcv macrocytosis management pathophysiology pressure pulse acidosis aplastic approach celiac cirrhosis color discoloration disease elevation gastroenterology hepatology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Volume (<80 fL) • Iron ... Poisoning • Anemia ... Marrow Failure • Anemia ... #MCV #Classification
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Overall Approach to Anemia ... Reticulocytes, MCV ... • Aplastic Anemia ... • Anemia of Chronic ... Non-lmmune #Anemia
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
Causes of Anemia ... ) - Differential ... Diagnosis Algorithm ... TlBC > 18% • Anemia ... #Microcytic #Anemia
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
for Anemia (Morphological ... Microcytic" • Iron ... thalassemia • Anemia ... #differential # ... diagnosis #causes
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... Corpuscular Volume (MCV ... (MAHA) - Abnormal ... Deficiency # ... Normocytic #Anemia
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Corpuscular Volume (MCV ... • Pernicious Anemia ... • Pernicious Anemia ... #Macrocytic #Anemia
Causes of Iron Deficiency • Inadequate Intake: Vegetarian/vegan diet, Malnutrition • Increased Body Needs: Infants/preschoolers, Pregnancy,
Causes of Iron Deficiency ... Pregnancy, EPO treatment ... Loss (without anaemia ... #Deficiency #differential ... #diagnosis #causes
Causes of Wide Pulse Pressure - Differential Diagnosis Physiologic: • Advanced age-arteriosclerosis (less compliant arteries) • Well
hypovolemia - Severe iron ... deficiency anemia ... viscosity) - anemia ... #Diagnosis #causes ... #cardiology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
- Differential ... Diagnosis Algorithm ... effect following treatment ... malignancy • Iron ... deficiency anemia
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... and petechiae Causes ... Treatment: ... oncology #hematology #diagnosis
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