13 results
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus
Clinical and Immunologic Criteria

CLINICAL CRITERIA
 - ACUTE CUTANEOUS LUPUS
Criteria - Systemic Lupus ... Erythematosus Clinical and Immunologic ... ACUTE CUTANEOUS LUPUS ... CHRONIC CUTANEOUS LUPUS ... <100,000/MM3) IMMUNOLOGIC
Anaphylaxis: Pathogenesis
Anaphylaxis is a Type 1 hypersensitivity reaction
While the primary mechanism of anaphylaxis is mast cell
cell activation, basophils ... pathophysiology #immunology
Inflammatory mechanism of asthma. 
Airway epithelial cells exposed to activation stimuli, including allergens, viruses, and irritants,
mast cells, and basophils ... mast cells and basophils ... #inflammatory #immunology
Type III Hypersensitivity: Pathogenesis and clinical findings
Definition: Small antigen-antibody complexes (produced from normal immune response to
: • Systemic Lupus ... HypersensitivityReaction #Allergy #Immunology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
Criteria for Systemic Lupus ... cutaneous or discoid lupus ... Acute cutaneous lupus ... Class II or V lupus ... nephritis Immunologic
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... , oral ulcers, Lupus ... Cytopenia: Common • Immunologic ... Lupusreference #SLE #lupus
Evaluation of Leukocytosis:
The term 'leukocyte' applies to any cells within the myeloblast, monoblast, & lymphoid lineages.
Include
cells within the myeloblast ... eosinophils, & basophils ... NEUTROPHILS #WCC #BASOPHILS
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... Drug Induced Lupus ... Epidemiology: -10% of all lupus ... drug-dependent) • Immunologic ... Cytopenia: Common • Immunologic
Causes of Interstitial Lung Disease - Differential Diagnosis Algorithm
Idiopathic Interstitial Pneumonia
 • (UIP) Usual Interstitial Pneumonia
Hypersensitivity Pneumonia - Immunologic ... Arthritis, Systemic Lupus
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
eosinophilia, basophilia ... Neutrophils • Immature/Myeloblasts