89 results
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
Basophilia - Differential ... Causes: • Iron deficiency ... #Differential # ... Diagnosis #causes #hematology ... #basophils
Approach to Leukocytosis - Differential Diagnosis Algorithm

Features of hematologic malignancy:
 • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
Leukocytosis - Differential ... Features of hematologic ... after initial Rx), basophilia ... #Leukocytosis #Differential ... Diagnosis #Algorithm #hematology
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm
Sequestration:
 • Splenomegaly
Marrow Infiltration:
 • Hematologic and non-hematologic
Pancytopenia - Differential ... Infiltration: • Hematologic ... and non-hematologic ... Myelodysplasia Nutritional deficiency ... #Neutropenia #Differential
Erythroderma - Diagnostic Algorithm. Pathophysiology: 1) Extensive cutaneous capillary dilation, results in widespread exfoliation of the
Pathophysiology: ... Eosinophils 3) Basophils ... #Diagnosis #Dermatology ... Nikolsky #Algorithm #Differential
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... thalassemia, S Lepore • Basophilic ... ' nucleotidase deficiency ... Hemolytic #Anemia #Differential ... Algorithm #workup #hematology
Polycythemia (Erythrocytosis) - Pathophysiology

#Polycythemia #Erythrocytosis #Pathophysiology #hematology #algorithm #differential #diagnosis
Erythrocytosis) - Pathophysiology ... Erythrocytosis #Pathophysiology ... #hematology #algorithm ... #differential #
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Bite cells: G6PD deficiency ... , Thalassemia Basophilic ... Smear #Analysis #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Thrombocytosis - Differential ... Non malignant hematologic ... states • Non-hematologic ... malignancy • Iron deficiency ... Thrombocytosis #Differential
Common RBC Inclusions and Associations
 • Howell Jolly Bodies: Hyposplenism, Asplenism, Severe hemolytic anemia
 • Heinz
Heinz Bodies: G6PD deficiency ... Hemoglobin H disease • Basophilic ... Bodies #diagnosis #hematology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased Heme Synthesis or
Volume (MCV) - Differential ... RBC>13 • Iron Deficiency ... MCV/RBC<13, +/- basophilic ... #elevatedMCV #Differential ... Algorithm #Causes #Hematology