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differential proteinuria hematuria nephritis renal syndrome atlas biopsy blood classification glomerulonephritis indications interpretation interstitial key lupus membranoproliferative mpgn sle syndromes
Nephritic vs Nephrotic Syndrome Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes. Step
casts or dysmorphic ... RBCs in urine)? ... #Syndrome #Comparison ... #Algorithm #Nephrology ... #Diagnosis
Glomerular Diseases - Nephritic and Nephrotic Syndromes Nephritic syndrome—due to GBM disruption. Hypertension. t BUN and creatinine.
Glomerular Diseases ... RBC casts in urine ... severe cases ... may be in nephrotic ... #Diseases #Nephritic
Causes of Hematuria - Differential Diagnosis Algorithm Red blood cells on urine microscopy. Must exclude false positives
blood cells on urine ... and/or RBC casts ... • Hereditary nephritis ... and >3.5g/day (nephrotic ... #Algorithm #Causes
Algorithmic Approach to Acute Interstitial Nephritis When to suspect AIN? (not sensitive) • AKI, AKD, rapidly progressive
Nephritis When ... casts/RTE; blend ... #Interstitial #Nephritis ... #AIN #Algorithm ... #nephrology #diagnosis
Lupus Nephritis - Diagnostic approach to kidney disease associated with systemic lupus erythematosus (SLE) SLE patient develops
Lupus Nephritis ... urine sediment ... , RBC casts, WBC ... casts) especially ... #diagnosis #algorithm
Urine Microscopy - Casts Acellular Casts • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... suggestive of nephrotic ... ) • Granular Casts ... • RBC Casts - ... #Urine #Microscopy
Urinary Casts and Disease Associations Hyaline - May be nonspecific; seen in normal individuals or during severe
Urinary Casts and ... in acute tubular ... tubulointerstitial nephritis ... tuberculosis Fatty - Nephrotic ... #Diagnosis #Nephrology
Atlas of Urine Microscopy Findings • Epithelial cells - Normal • Renal tubular cells - Acute
Atlas of Urine Microscopy ... • Red cell casts ... glomerular disease ... • Granular casts ... #nephrology #casts
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
• Drugs Glomerular ... sediment - WBC/ ... RBC casts ... Minimal change disease ... #Algorithm #Causes
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
sediment Microscopic ... sediment by microscopy ... casts → Diagnostic ... disease Renal ... #nephrology #renal
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