23 results
Pathologic Red Blood Cell (RBC) Morphologies and Associated Diseases

Acanthocyte (spur cell),  
Basophilic stippling, 
Bite cell,
Pathologic Red Blood ... cell, Other RBC ... Morphologies #Key #Atlas #Microscopy ... #Pathology #Hematology ... #Dyspmorphic #BloodSmear
Here are very large, immature myeloblasts with many nucleoli. A distincitve feature of these blasts is
large, immature myeloblasts ... Clinical #Path #BloodSmear ... #Blood #Smear # ... Microscopy #Auer
A normal peripheral blood smear indicates the appropriate appearance of red blood cells, with a zone
normal peripheral blood ... appearance of red blood ... the size of the RBC ... Clinical #Path #Microscopy ... PeripheralBloodSmear #BloodSmear
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
Antibody Autoimmune Hemolytic ... reticulocytes • Hemolysis ... ↑ LDH • Anti-RBC ... type ± C3d • Blood ... management #treatment #rheumatology
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood ... Microangiopathic hemolytic ... #Peripheral #Blood ... Smear #Analysis #hematology ... #microscopy #interpretation
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... disease, McLeod blood ... Microangiopathic Hemolytic ... differential #diagnosis #hematology ... #microscopy #atlas
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... microangiopathic hemolytic ... Microangiopathic hemolytic ... #anemia #Hematology ... Pathology #Smear #Microscopy
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
the peripheral blood ... > 3: • Acute blood ... Retroperitoneal, Uterine • Hemolysis ... Microangiopathic hemolytic ... Production #Index #hematology
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
of peripheral blood ... on the left Myeloblast ... Even with normal WBC ... cultures, including blood ... #CBC #hematology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... 2) External (RBC ... - Peripheral Blood ... Urobilinogen #Hemolysis ... Differential #Diagnosis #hematology