13 results
diagnosis anemia causes hemolytic lfts extravascular intravascular transaminitis abnormal acute agglutinin anemias antibody chemistry cold disease elevated interpretation liverenzymes liverfunctiontests
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
- Differential ... (AIHAs) • Alloimmune ... • Extrinsic RBC ... • Intrinsic RBC ... #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Immune-Mediated • Warm AIHA ... • Cold AIHA ... • Drug-induced AIHA ... elliptocytosis - RBC ... #Causes #Hematology
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
1) DIAGNOSE AIHA ... ↑ LDH • Anti-RBC ... • Blood smear: Differential ... screening 3) TREAT AIHA ... #diagnosis #management
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... 2) External (RBC ... : Warm AIHA, Cold ... AIHA, Transfusion ... Diagnosis #hematology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
: Autoimmune hepatitis ... , PBC, PSC, IgG4 ... • LDH: Heart, RBC ... #injury #hepatitis ... #hepatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
(AIHA) "Warm" ( ... (AIHA)"Cold" (usually ... • Intrinsic RBC ... Extravascular #Causes #differential ... #diagnosis #hematology
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
Autoimmune Hepatitis ... been reported (eg AIH-PBC ... If suspected, AIH ... #Hepatitis #AIH ... #Hepatology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Injury - Differential ... Other: NAFLD, Autoimmune ... Malignancy, 1° PBC ... #Injury #Differential ... #hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Viral, Ischemia, AIH ... - Viral, AIH ... Alcohol, Viral, HH, AIH ... Ducts - PBC ... #diagnosis #hepatology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach ... Spherocytosis, G6PD, PK, HbC ... - Extrinsic: Autoimmune ... Non-megaloblastic: Liver ... Diagnosis #hematology
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