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diagnosis differential oncology anemia causes management workup algorithm leukemia chronic cll disease hemolytic lymphocytic macrocytic rbc agglutinin aplastic arthritis atlas
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Blood Disorders ... , Auer rod • Lymphoid ... bcr-able (+) ↑ WBC ... @AmyChung #Blood ... #Disorders #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Lymphocytosis on CBC ... lymphoproliferative disorders ... Lymphocytosis: Absolute blood ... microglobulin Treatment ... workup #oncology #hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... disease, McLeod blood ... Bite Cell RBC: G6PD ... Unstable hemoglobin disorders ... differential #diagnosis #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Artifact (redo CBC ... • Rheumatic disorders ... effect following treatment ... Iron deficiency anemia ... Algorithm #Causes #Hematology
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
of peripheral blood ... Left Shift: • Cell ... precursors" • Stab cell ... on the left Myeloblast ... #CBC #hematology
Consensus Indications for Irradiated RBC Transfusions: Cellular blood components are irradiated for the prevention of TA-GVHD. Transfused
immunodeficiency disorders ... Immunodeficiency Disorder ... Patients with Hodgkin Lymphoma ... Hematopoietic stem cell ... #Indications #Hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
leukemia in adults • Disorder ... lymphocytes, smudge cells ... Vmphocytosis on routine CBC ... lymphoma (Richter ... Leukemia #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
the peripheral blood ... - Blood and Bone ... Neutrophils • Immature/Myeloblasts ... - infiltrates (anemia ... #Hematology #Oncology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
decreased PLT count: CBC ... plateletcount), peripheral blood ... changes), high MCV anemia ... or if a primary hematologic ... Causes #Workup #hematology
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Mean corpuscular (cell ... Red cell distribution ... High in acute blood ... (BM) ablative disorders ... Diagnosis #Workup #Hematology
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