13 results
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
RBC casts in urine ... severe cases ... #Classification ... #Proteinuria #Nephrology ... #Diagnosis
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
hematuria (RBC casts ... urine)? ... #Syndrome #Comparison ... #Algorithm #Nephrology ... #Diagnosis
Algorithmic Approach to Acute Interstitial Nephritis
When to suspect AIN? (not sensitive)
 • AKI, AKD, rapidly progressive
sterile pyuria, WBC casts ... eosinophiluria, microscopic ... , granular casts ... #Nephritis #AIN ... #Algorithm #nephrology
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
sediment Microscopic ... hematuria: - RBC casts ... microscopic and ... #causes #urology ... #nephrology #renal
Atlas of Urine Microscopy Findings
 • Epithelial cells - Normal
 • Renal tubular cells - Acute
Atlas of Urine Microscopy ... fresh at time of microscopy ... • Red cell casts ... #Microscopy #Atlas ... #nephrology #casts
Urine Microscopy - Casts
Acellular Casts
 • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... suggestive of nephrotic ... #Urine #Microscopy ... #nephrology #interpretation ... #diagnosis
Urinary Casts and Disease Associations
Hyaline - May be nonspecific; seen in normal individuals or during severe
Urinary Casts and ... heme-granular casts ... edgarvlermamd - Nephrology ... #Differential #Microscopy ... #Diagnosis #Nephrology
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm
Acute Kidney Injury (AKI) - Acute increase
Epithelial cell casts ... polyangiitis /microscopic ... Nephritis • Drugs ... #AKI #Acute #KidneyInjury ... #Nephrology #Differential
Hematuria Workup and Diagnosis Algorithm
 • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
, RBC casts, dysmorphic ... → Refer to Nephrology ... and referral to Urology ... cystoscopy • Refer to Nephrology ... Algorithm #Workup #urology
Simplified Approach to Acute Kidney Injury (AKI)
1) IS THIS AN EMERGENCY? 
Is there a dialysis indication
require urgent nephrology ... PROBLEM ~80% of AKI cases ... Assess UA w/ microscopy ... for WBCs, RBCs, casts ... #nephrology