15 results
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
Glomerular Diseases ... RBC casts in urine ... Nephrotic #Syndromes #Classification ... #Proteinuria #Nephrology ... #Diagnosis
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
hematuria and/or proteinuria ... the patient have glomerular ... dysmorphic RBCs in urine ... #Algorithm #Nephrology ... #Diagnosis
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... - Differential Diagnosis ... • Drugs Glomerular ... #Nephrology #Differential ... #Diagnosis #Algorithm
Hematuria Workup and Diagnosis Algorithm
 • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
Hematuria Workup and Diagnosis ... • Evidence of glomerular ... bleeding (proteinuria ... → Refer to Nephrology ... cystoscopy • Refer to Nephrology
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
- Differential Diagnosis ... → Diagnostic of ... - Proteinuria ... #causes #urology ... #nephrology #renal
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
arbitrarily defined as urine ... because nephritic urine ... Nephrocalcinosis causes ... #glomerular #proteinuria ... nephrotic #syndrome #nephrology
Management of Lupus Nephritis
Lupus nephritis (LN) in 10 to 40% of SLE
Hallmark = proteinuria 20.5 g/g
SLE Hallmark = proteinuria ... therapy Goal: proteinuria ... Focal LN (<50% of glomeruli ... #treatment #management ... #rheumatology #nephrology
Recommended initial testing for patients being evaluated for glomerular disease 

24-hour urine collection - Quantify proteinuria.
disease 24-hour urine ... Serum or urine for ... infections are common causes ... testing #workup #diagnosis ... nephrotic #nephritic #nephrology
Recommended initial testing for patients being evaluated for glomerular disease
1) 24-hour urine collection - Quantify proteinuria.
disease 1) 24-hour urine ... Serum or urine for ... infections are common causes ... #workup #diagnosis ... initial #testing #nephrology
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN
 • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
GN • Active Urine ... , +/- proteinuria ... formation along glomerular ... Glomerulonephritis #MPGN #nephrology ... #diagnosis #renal