29 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... Lymphadenopathy AML ... Neutrophils • Immature/Myeloblasts ... cutaneous plaques) AML ... #Hematology #Oncology
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
promyelocytic leukemia ... I see all of these ... promyelocytic #leukemia ... #APL #APML #Pathology ... #Hematology #Clinical
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
Anticoagulant Medications ... RA, SLE), Post-partum ... promyelocytic leukemia ... comparison #diagnosis #hematology ... #deficiency
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Leukemia, Tumour ... Megakaryopoiesis • B12 Deficiency ... • Folate Deficiency ... Autoimmune • ITP • SLE ... Algorithm #Causes #Hematology
Coagulation Cascade and Anticoagulant Sites of Action

- Amy Chung, MD, MSc https://twitter.com/AmyChung

#AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
of Action - Amy ... Anticoagulants #Medications ... #Pharmacology # ... Mechanisms #DOAC #Hematology
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
Measurement in SLE ... Best indications ... #Measurement #SLE ... #rheumatology # ... pharmacology #levels
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
Chronic myeloid leukemia ... (CML) - associated ... Acute myeloid leukemia ... Causes: • Iron deficiency ... Diagnosis #causes #hematology
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
specifically: iron deficiency ... Chronic myeloid leukemia ... (CML) - Dr. ... Diagnosis #Causes #hematology
Atopic Dermatitis - Topical Treatment Options 
First Line: Topical Corticosteroids 
  - High Potency: Betamethasone
After non-pharmacologic ... Remember that all ... than roflumilast (see ... #Pharmacology # ... Dermatology #Management
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic Leukemia ... non-Hodgkin lymphoma SLL ... • Most common leukemia ... Transform to DLBCL, PML ... workup #oncology #hematology